Wikipedia reports: She played Quorra in Disney’s Tron: Legacy, which opened on December 17, 2010. In the December 2010/January 2011 issue of Details Wilde was quoted as saying she panicked the first time she saw her costume for the movie: “I saw the boobs on the suit and I said, ‘Oh hell no. I’m doing kicks and backflips in this thing?’” She also reprised her role as Quorra in Tron: Uprising in the episode “Isolated”. She was seen in flashbacks of Paige’s past, where she befriended Quorra, not knowing that she was an ISO (isomorphic algorithm) at the time.
Wilde played Ella Swenson in the science fiction Western film Cowboys & Aliens. Her character works with Jake Lonergan (Daniel Craig), and Woodrow Dolarhyde (Harrison Ford), to save their town from evil aliens. Wilde played Sabrina McKay in the comedy film The Change-Up. Her character is the love interest of Mitch Planko, who was played by Ryan Reynolds. In January 2011, it was announced that Wilde was cast alongside Chris Pine in the film People Like Us, released in June 2012.
In August 2011, it was announced Wilde would be leaving House to pursue her film career. Wilde left House a few months later, in the episode “Charity Case”. In May 2012, Wilde returned to House for the final two episodes, “Holding On” and “Everybody Dies”. The New York Observer has described Wilde as having a “throaty voice” and the “wide, teal-eyed charisma of Hollywood in the days of yore”. She has cited Meryl Streep, Sigourney Weaver, Frances McDormand, Catherine Keener and Robin Wright Penn as acting inspirations.